Relevance: The detection rate of primary heart tumors in cardiac surgery clinics ranges from 0.09% to 1.9% of the total number of hospitalized patients. Cardiac myxomas account for up to 75% of heart tumors.

The purpose of the study is to present unusual cases of diagnosis and treatment of rare heart tumors.

Material and methods: At the M.M. Amosov National Institute of Cardio-Vascular Surgery of the National Academy of Medical Sciences of Ukraine for the period from 01.01.1969 to 01.01.2024 - 1033, patients were operated on for primary heart tumors. Cardiac myxomas (CM) were detected in 923 (89.4%) patients, of which in 811 (87.9%) cases there were myxomas of the left atrium (LA), myxomas of the right atrium (RA) were detected in 84 (9.0%) The age of patients with SM ranged from 3 to 79 years (mean 48.4±3.4 years), of which 653 (72.4%) were aged from 31 to 60 years. Non-myxomas benign cardiac tumors were observed in 40 (3.9%) cases. Malignant cardiac tumors were observed in 70 (6.8%) cases. Non-myxomas benign cardiac tumors included leiomyofibromas, fibromas, rhabdomyomas, hemangiomas, lipomas, and papillary fibroelastomas. Of greatest interest are the diagnosis and treatment tactics of leiomyofibromas, hemangiomas, and lipomas, the features of which we present in this study. Among the malignant tumors of the heart were sarcomas of many types: angio-, fibro-, chondro-, myxo-, liposarcoma, as well as lymphomas and malignant fibrous histiocytoma, metastases of kidney cancer and semenomas. Of particular interest are the diagnosis and treatment tactics of Burkitt's lymphoma and semenoma.

Results: In-hospital mortality over the past 22 years during surgical treatment of CM was 0%, that is, 559 operations were performed without fatal consequences. In-hospital mortality in the treatment of non-myxoma benign cardiac tumors was 2.5% (1 case). In-hospital mortality in the treatment of malignant cardiac tumors was 18.6% (13 cases).

Conclusion: To diagnose benign and malignant tumors of the heart, it is necessary to carry out a set of instrumental diagnostic methods that determine the tactics, often individual, of surgical treatment of this pathology.

Keywords: non-myxoma benign and malignant tumors of the heart, cardiac myxomas, surgical treatment.

Volodymyr V. Isaienko (10.07.1961, Kyiv). Education in the Kiev Medical Institute named O.O. Bogomolets in 1984; worked as a surgeon in Kyiv’s clinic № 1. From 1988 worked in the M.M. Amosov National Institute of Cardio-Vascular Surgery of the National Academy of Medical Sciences of Ukraine as a doctor-surgeon. He has a higher qualification category in the field of "Surgery of the heart and main vessels". He defended 2005 his Ph.D. thesis on the topic: "Surgical correction of mitral valve lesions in infectious endocarditis".Since 2001, He works as an Associate Professor of the Department of Cardiac and Main Vessels Surgery at the National University of Health Care named P.L. Shupik, existing on the base of the M.M. Amosov National Institute of Cardio-Vascular Surgery, received his academic title in 2013. He is the author of more than 150 scientific articles on various aspects of cardiac surgery, and has 15 author's certificates for inventions He is a member of the Association of Cardiovascular Surgeons of Ukraine