Impaired glucose metabolism and its consequence diabetes mellitus is still challenging the health care system worldwide. According to the International Diabetes Federation in 2021, the number of adult people living with diabetes was approximately 537 million and 860 million adults had prediabetes. It is predicted that numbers

will rise in the future. Numerous researches have shown that prediabetes and diabetes mellitus are serious risk factors for cardiovascular diseases. Lots of epidemiological evidence figured out that diabetes mellitus is associated with the risk of

developing heart failure. Diabetes mellitus is highly prevalent among patients with heart failure. Moreover, several anti-diabetics (anti-prediabetic) medications are contributing their share into developing heart failure by increasing risk of mortality and hospitalization for heart failure. HF is still a significant factor in life expectancy, especially among diabetic patients. HF can be viewed as both a cause and a complication of DM at the same time. Evidence strongly suggest that there is negative predictive effect of DM in the course of HF.  Therapy for this category of patients should be characterized by a holistic approach, including a thorough glycemic control  

as well as an effective blockade of neurohumoral changes. New pharmacological options, such as SGLT2 inhibitors, are allowing for better control of this life-threatening T2D condition. Biomarkers like NT-proBNP can help identify HF early and predict prognosis and therapeutic efficacy of HF or/and diabetes treatment. As a result, NT-proBNP testing should be used early in the monitoring of subjects with diabetes with a high CV risk.

Natavan Ismayilova has completed her PHD at the age of 35 from Azerbaijan Medical University. She is cardiologist and has experience in both inpatient and outpatient setting. She has over 50 publications in local and international peer-reviewed journals. Her main interest areas are heart failure, atrial fibrillation, coronary artery diseases and risk factors.