Md. Rezaul AlamM. Abdur Rahim Medical College, Bangladesh
Title: Lipid Profile of Coronary Heart Disease Patients: A Prospective Observational Study
Background: Coronary heart disease remains the major cause of mortality & morbidity
in the entire world population despite therapeutic advances that control many risk factors.
Lipid profile is regarded as an important factor in the development of coronary heart disease (CHD). There have been numerous studies confirming the association of hyperlipidemias with CHD in most of the Western world & as well as Asian countries of the world. But we have little data on the relation between CHD & lipid profile.
Aim of the study: The aim of this study was to assess abnormal lipid levels & their association with CHD.
Methods: A comparative observational study was conducted at the department of cardiology in M. Abdur Rahim Medical College, Dinajpur, Bangladesh from January 2019 to December 2019.
Properly written consent was taken from all the participant before starting the main part of the investigation. Obeying inclusion & exclusion criteria of the study, a total 131 participant were finalized as the study population. Among case group which was formed with 90 patients who had coronary heart disease (CHD) and with 41 healthy people, the control group was formed. All necessary data was collected, analyzed and disseminated by several programs of MS office and SPSS versions 23.
Result: The study was conducted with 90 case group participant & 41 control group participant.
Among the case group 78% were male and 22% were female. The study showed serum cholesterol concentration and HDL concentration were significant between the case and control groups in all age groups and the P-value was less than 0.0001 in every age group. Triglyceride concentration was significant between case and control groups in 41-50 & 51-60 years age group with a P-value less then 0.0001. But in the age group more then 60 years we did not find any significant correlation and there the P-value was 0.478. LDL concentration between groups showed. Significant correlation between case and control groups in the age groups between 41-50 & 51-60 years where P-value found less then 0.0001 and 0.0002 respectively. But in the age group more then 60 years we did not find any significant correlation, where the P-value was 0.515.
Conclusion: In the study it was found that total cholesterol, LDL cholesterol and triglyceride were significantly higher in coronary heart disease (CHD) patients. But HDL cholesterol was significantly low.