Angiotensin-converting enzyme inhibitors dose optimizations (ACEIs) are essential to boost the treatment outcome in heart failure patients (HF) with reduced ejection fraction. the main purpose of this study was to evaluate dose optimization and associated factors of ACEIs. An institutional-based retrospective study was conducted. A systematic random sampling method was carried out. Only one-third of patients received the optimum dose of ACEIs. Older age and dose of furosemide greater >40 mg were significantly associated with  suboptimal dosing of ACEIs. 

Abebech Tewabe has completed her  under gratuate degree in B.pharma at the age of  23 and her masters in clinical pharmacy at the age of 27 years from University of Gondar, Ethiopia. She is the cordinator of ambulatory ward attachement and suergery ward in the department of clinical pharmacy, Gondar. she has over 5 publications that have been cited over 75 times. She has participated in different activities which in cludes in grant mega project and community service. she has been serving a member of reviewor for several reputed journals.