Abhinav Banerjee
Abhinav Banerjee, IndiaPresentation Title:
Use of blood gas analyzer (ABG) and laboratory autoanalyzer (AA) to measure electrolytes in Intensive care unit patients: A Comparative study and finding correction factor
Abstract
Use of blood gas analyzer (ABG) and laboratory autoanalyzer (AA) to measure electrolytes in Intensive care unit patients: A Comparative study and finding correction factor.
Objectives:
To investigate whether electrolyte levels measured by using blood gasanalyzers (ABG) and auto- analyzers (AA) are equivalent and can be used interchangeably or not.
Methods:
We have prospectively studied 100 samples of patients hospitalized in ICU. Arterial blood samples was collected in heparinized blood–gassyringes and analysed using ABL 800 basic blood–gas analyser which employs direct ISE technology. We took a further sample at the same time, from the same arterial line samples and send, to our central laboratory, where serum Sodium and Potassium concentrations were analyzed via indirect ISE on a Beckman Coulter AU640 MODEL
Results:
The mean sodium level measured by ABG was 126.25 ± 6.06 m mol/L and AA was 135.59 ± 5.91 m mol/L. The Pearsons correlation coefficient was 0.92. The Bland Altman limits of agreement was 0.145 – 0.350 mmol/lit. The mean potassium level measured by ABG was 3.542 ± 0.76 m mol/L and AA was 4.196 m ± 0.72 m mol/L . The Bland altmans comparison limits was -0.97 - 10.05 mmol/lit and associated pearson correlation coefficient was 0.928
Conclusions:
We conclude that the ABG and AA do not yield equivalent Na+ and K+ data and are not interchangable . Concordance between ABG and LAB should be established the following correction.
a) Sodium: Current difference = 9.34, standard error = 0.846
95% Class interval = 7.671 to 11.009
Correction factor: - 2 – 5% calibration
b) Potassium: Current difference = 0.654, standard error = 0.1047
95% Class interval = 0.4475 to 0.8605
Correction factor: - 0.2 – 0.5% calibration
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